Protein is really important for dieting success, right? Anyone who has interested in the science of dieting knows this, but recent research from Bettina Mittendorfer, Research Associate Professor at Washington University in St. Louis’s School of Medicine, and colleagues published in Cell Reports has raised doubts that protein is indeed a wholly-helpful solution. To shed light on this study and its findings, I invited Dr. Stephan Guyenet to join humanOS Radio for a conversation. Perhaps no other person has done more in the last few years to help the general public, and even health professionals, understand the true meaning of new research dealing with energy regulation and weight control.
Biologists have known for nearly a century that some types of cancer cells consume significantly more glucose than normal cells.
Regular cells burn most of a sugar molecule in their mitochondria in order to make energy, which is why mitochondria are often referred to as cellular “power plants.”
Cancer cells, however, function quite differently. They rely heavily upon another energy-producing process in the metabolism of sugar called glycolysis. This produces energy faster, but also extracts much less of it from the sugar molecule. Cancer’s preference for glycolysis has been dubbed the “Warburg effect,” after German physiologist, and Nobel Prize winner, Otto Warburg, who was the first to demonstrate it experimentally.
It has never been entirely clear why the difference exists. Cancer cells presumably need a considerable amount of energy in order to grow and proliferate throughout the body. How do they do it?
In the previous article on aging, we looked at three forms of dietary restriction: caloric restriction, prolonged fasting, and alternate-day fasting. These interventions have played an important role in providing a framework for researchers to begin unraveling the molecular details of how aging happens. But these dietary restrictions are quite extreme and are simply not practical for everyone. In this article, we will look at two less extreme forms of dietary restriction: protein restriction, and the Daniel fast.